Early Menopause Is a Risk Factor for Postmenopausal Depression in Healthy Women, But Are Depressive Episodes a Risk Factor for Early Menopause?

Sermin Kesebir, Sinem Metin, Meltem Dilek Tasdemir Erinc, Ahmet Yosmaoglu

Abstract


Background: This study investigated whether age of menopause in bipolar women is different from that in healthy women and if there is a relationship between age at menopause and previous depressive episodes.

Methods: We consecutively evaluated 86 euthymic and postmenopausal women who were older than 33 years and were diagnosed with bipolar disorder according to Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV). The healthy control group comprised 100 individuals of similar age. After the diagnostic interview, bipolar patients completed the Mood Disorders Diagnosis and Follow-Up Form (SKIP-TURK).

Results: Age at menopause in bipolar women was earlier than that of the controls (P = 0.001). Age at menopause correlated with age of onset of bipolar disorder (r = 0.453). A strong inverse correlation was found between the age of menopause and total duration of depressive episodes (r = -0.542).

Conclusion: Early-onset bipolar disorder is associated with early ages of menopause. Age at menopause seems to be related to duration of depressive period. Considering the effects of hypoestrogenemia on ischemic heart diseases and cognitive impairment, it is important that the risk which is already high for both situations should be reduced, and depressive periods should be prevented.




J Clin Gynecol Obstet. 2018;7(3-4):69-71
doi: https://doi.org/10.14740/jcgo504w

 


Keywords


Age at menopause; Depressive episode; Bipolar disorder; Ischemic heart disease; Cognitive impairment

Full Text: HTML PDF
 
Home     |     Log In     |      About     |      Search     |      Current     |      Archives     |      Submit      |     Subscribe


 

     

Aims and Scope

Current Issues

Conflict of Interest

About Publisher

Editorial Board

Archives

Copyright

Company Profile

Editorial Office

Misconduct and Retraction

Permissions

Company Registration

Contact Us

Abstracting and Indexing

ICMJE

Ownership

Instructions to Authors

Access

Declaration of Helsinki

Contact Publisher

Submission Checklist

Reprints

Terms of Use

Company Address

Submit a Manuscript

Open Access Policy

Privacy Policy

Browse Journals

Publishing Fee

Publishing Policy

Disclaimer

Recent Highlights

Peer-Review Process

Publishing Quality

Code of Ethics

Advertising Policy

Manuscript Tracking

Advanced Search

For Librarians

Careers

Publishing Process

Publication Frequency

For Reviewers

Propose a New Journal

       
       

Journal of Clinical Gynecology and Obstetrics, quarterly, ISSN 1927-1271 (print), 1927-128X (online), published by Elmer Press Inc.        
The content of this site is intended for health care professionals.
This is an open-access journal, the authors retain the copyright, the journal is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International
License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
Creative Commons Attribution license (Attribution-NonCommercial 4.0 International CC-BY-NC 4.0)


This journal follows the International Committee of Medical Journal Editors (ICMJE) recommendations for manuscripts submitted to biomedical journals,
the Committee on Publication Ethics (COPE) guidelines, and the Principles of Transparency and Best Practice in Scholarly Publishing.

website: www.jcgo.org   editorial contact: editor@jcgo.org
Address: 9225 Leslie Street, Suite 201, Richmond Hill, Ontario, L4B 3H6, Canada

© Elmer Press Inc. All Rights Reserved.

DECLARATION: THIS JOURNAL SITE OUTLOOK IS DESIGNED BY THE PUBLISHER AND COPYRIGHT PROTECTED. DO NOT COPY!