Journal of Clinical Gynecology and Obstetrics, ISSN 1927-1271 print, 1927-128X online, Open Access
Article copyright, the authors; Journal compilation copyright, J Clin Gynecol Obstet and Elmer Press Inc
Journal website http://www.jcgo.org

Original Article

Volume 4, Number 2, June 2015, pages 217-225

A Clinical Experience to Assess Safety and Efficacy of Fixed Dose Combination of Clindamycin and Clotrimazole in the Treatment of Patients With Mixed Bacterial and Fungal Vaginosis

Figures

Figure 1.
Figure 1. Changes in the number of patients with vaginal discharge consistency after the treatment.
Figure 2.
Figure 2. Changes in the number of patients with vaginal discharge odor after treatment.
Figure 3.
Figure 3. Changes in mean score of vaginal burning after treatment.
Figure 4.
Figure 4. Changes in vaginal irritation score after treatment.
Figure 5.
Figure 5. Changes in patients with vulvar erythema after treatment.
Figure 6.
Figure 6. Change in patients with vaginal erythema post-treatment.
Figure 7.
Figure 7. Change in cervical erythema post-treatment.
Figure 8.
Figure 8. (a) Global assessment of efficacy by physician. (b) Global assessment of efficacy by patient.
Figure 9.
Figure 9. (a) Global assessment of tolerability by physician. (b) Global assessment of tolerability by patient.

Tables

Table 1. Demographical Data
 
Parameters
No. of cases486
Age (years)
  Mean32.19
  SD5.35
  Range21.00 - 48.00
Weight (kg)
  Mean62.12
  SD7.58
  Range41.00 - 77.50

 

Table 2. Physical Examination Parameters
 
Physical examinationMean ± SD (N = 486)
Temperature (° F)97.91 ± 0.68
Pulse rate (/min)76.09 ± 3.17
Respiratory rate (/min)17.69 ± 3.03
SBP (mm Hg)121.22 ± 6.79
DBP (mm Hg)88.64 ± 6.31

 

Table 3. Profile of Adverse Events
 
Adverse eventsNo. of cases (N = 486)Percentage
Abdominal cramps10.2
Burning51.0
Diarrhea10.2
Frequent urination20.4
Headache10.2
Itching51.0
Rash10.2
Vaginal pain40.8
No. of events204.1
No. of cases183.7