J Clin Gynecol Obstet

Journal of Clinical Gynecology and Obstetrics, ISSN 1927-1271 print, 1927-128X online, Open Access

Article copyright, the authors; Journal compilation copyright, J Clin Gynecol Obstet and Elmer Press Inc

Journal website http://www.jcgo.org

Original Article

Volume 5, Number 1, March 2016, pages 27-31

Are Neutrophil/Lymphocyte Ratio and Platelet/Lymphocyte Ratio Predictors for Severity of Preeclampsia?

**Table 1.** Baseline Characteristics of Pregnant Women With Preeclampsia and Those Without Preeclampsia
	Preeclampsia	Normal pregnant	P
BP: blood pressure.
Age	29.4 ± 6.1	28.6 ± 6.4	0.7
Gestational week	36.8 ± 2.0	37.2 ± 2	0.7
Birth weight (g)	2,229.2 ± 833.4	3,229.5 ± 615.4	< 0.001
APGAR1	6.8 ± 2.5	8.2 ± 1.8	< 0.001
APGAR5	8.3 ± 2.6	9.3 ± 1.7	< 0.001
Systolic BP (mm Hg)	163.7 ± 21.2	123.7 ± 10.2	< 0.001
Diastolic BP (mm Hg)	103.2 ± 10.8	79.1 ± 9.0	< 0.001
Protein in 24 h (g)	5.3 ± 0.6	7.3 ± 0.6	< 0.001

Table 1. Baseline Characteristics of Pregnant Women With Preeclampsia and Those Without Preeclampsia

Preeclampsia

Normal pregnant

BP: blood pressure.

Age

29.4 ± 6.1

28.6 ± 6.4

0.7

Gestational week

36.8 ± 2.0

37.2 ± 2

0.7

Birth weight (g)

2,229.2 ± 833.4

3,229.5 ± 615.4

< 0.001

APGAR1

6.8 ± 2.5

8.2 ± 1.8

< 0.001

APGAR5

8.3 ± 2.6

9.3 ± 1.7

< 0.001

Systolic BP (mm Hg)

163.7 ± 21.2

123.7 ± 10.2

< 0.001

Diastolic BP (mm Hg)

103.2 ± 10.8

79.1 ± 9.0

< 0.001

Protein in 24 h (g)

5.3 ± 0.6

7.3 ± 0.6

< 0.001

**Table 2.** Laboratory Parameters of Pregnant Women With Preeclampsia and Those Without Preeclampsia
	Preelampsia	Normal pregnant	P
AST: aspartat transmainase; ALT: alanine transaminase; LDH: lactate dehydrogenase.
AST (IU/L)	49.1 ± 122.3	35.3 ± 34.2	0.122
ALT (IU/L)	30.6 ± 52.2	26.4 ± 52.0	0.012
LDH (IU/L)	343.2 ± 348.7	240.5 ± 80.0	0.007
Creatinine	0.6 ± 0.2	0.5 ± 0.1	< 0.001
Hemoglobin (g/dL)	11.2 ± 1.7	11.8 ± 1.8	< 0.001
WBC (10³/μL)	13,643.4 ± 4,206.3	12,793.4 ± 3,882.6	0.214
Neutrophils (10³/μL)	11,731.0 ± 8,784.9	10,061.1 ± 3,903.2	0.107
Lymphocyte (10³/μL)	1,797.6 ± 636.4	1,964.9 ± 844.9	0.217
Platelet (10³/μL)	217,691.5 ± 67,343.6	217,195.7 ± 85,477.6	0.813
MPV (fL)	9.5 ± 1.1	9.1 ± 1.2	0.006
NLR	7.4 ± 5.2	7.2 ± 3.7	0.7
PLR	134.4 ± 64.5	130.5 ± 86.2	0.898

Table 2. Laboratory Parameters of Pregnant Women With Preeclampsia and Those Without Preeclampsia

Preelampsia

Normal pregnant

AST: aspartat transmainase; ALT: alanine transaminase; LDH: lactate dehydrogenase.

AST (IU/L)

49.1 ± 122.3

35.3 ± 34.2

0.122

ALT (IU/L)

30.6 ± 52.2

26.4 ± 52.0

0.012

LDH (IU/L)

343.2 ± 348.7

240.5 ± 80.0

0.007

Creatinine

0.6 ± 0.2

0.5 ± 0.1

< 0.001

Hemoglobin (g/dL)

11.2 ± 1.7

11.8 ± 1.8

< 0.001

WBC (10³/μL)

13,643.4 ± 4,206.3

12,793.4 ± 3,882.6

0.214

Neutrophils (10³/μL)

11,731.0 ± 8,784.9

10,061.1 ± 3,903.2

0.107

Lymphocyte (10³/μL)

1,797.6 ± 636.4

1,964.9 ± 844.9

0.217

Platelet (10³/μL)

217,691.5 ± 67,343.6

217,195.7 ± 85,477.6

0.813

MPV (fL)

9.5 ± 1.1

9.1 ± 1.2

0.006

NLR

7.4 ± 5.2

7.2 ± 3.7

0.7

PLR

134.4 ± 64.5

130.5 ± 86.2

0.898

**Table 3.** Baseline Characteristics of Pregnant Women With Severe and Mild Preeclampsia
	Mild preeclampsia (n = 27)	Severe preeclampsia (n = 66)	P
AST: aspartat transmainase; ALT: alanine transaminase; LDH: lactate dehydrogenase.
AST (IU/L)	18.0 ± 6.3	60.9 ± 142.1	0.001
ALT (IU/L)	13.0 ± 6.4	37.3 ± 60.0	0.013
LDH (IU/L)	208.8 ± 49.1	394.9 ± 398.0	< 0.001
Creatinine (mg/dL)	0.5 ± 0.2	0.7 ± 0.3	0.001
Hemoglobin (g/dL)	11.3 ± 1.8	12.0 ± 1.9	0.131
WBC (10³/μL)	12.9 ± 3.8	12.8 ± 3.9	0.931
Neutrophils (10³/μL)	10 ± 4.0	10.3 ± 3.8	0.680
Lymphocytes (10³/μL)	2.0 ± 0.9	1.8 ± 0.7	0.118
Platelets (10³/μL)	210.5 ± 91.4	234.3 ± 66.8	0.128
MPV (fL)	9.1 ± 1.1	9.1 ± 1.4	0.962
NLR	5.9 ± 3.5	6.8 ± 3.9	0.314
PLR	122.9 ± 92.0	149.8 ± 67.3	0.024
Maternal age (years)	30.6 ± 6.2	28.9 ± 6.1	0.345
Multiparous (%)
Systolic BP (mm Hg)	146.1 ± 4.7	170.8 ± 21.1	< 0.001
Diastolic BP (mm Hg)	93.9 ± 4.9	107.0 ± 10.2	< 0.001
GA at delivery (weeks)	35.0 ± 4.2	34.0 ± 3.9	0.160

Table 3. Baseline Characteristics of Pregnant Women With Severe and Mild Preeclampsia

Mild preeclampsia (n = 27)

Severe preeclampsia (n = 66)

AST: aspartat transmainase; ALT: alanine transaminase; LDH: lactate dehydrogenase.

AST (IU/L)

18.0 ± 6.3

60.9 ± 142.1

0.001

ALT (IU/L)

13.0 ± 6.4

37.3 ± 60.0

0.013

LDH (IU/L)

208.8 ± 49.1

394.9 ± 398.0

< 0.001

Creatinine (mg/dL)

0.5 ± 0.2

0.7 ± 0.3

0.001

Hemoglobin (g/dL)

11.3 ± 1.8

12.0 ± 1.9

0.131

WBC (10³/μL)

12.9 ± 3.8

12.8 ± 3.9

0.931

Neutrophils (10³/μL)

10 ± 4.0

10.3 ± 3.8

0.680

Lymphocytes (10³/μL)

2.0 ± 0.9

1.8 ± 0.7

0.118

Platelets (10³/μL)

210.5 ± 91.4

234.3 ± 66.8

0.128

MPV (fL)

9.1 ± 1.1

9.1 ± 1.4

0.962

NLR

5.9 ± 3.5

6.8 ± 3.9

0.314

PLR

122.9 ± 92.0

149.8 ± 67.3

0.024

Maternal age (years)

30.6 ± 6.2

28.9 ± 6.1

0.345

Multiparous (%)

Systolic BP (mm Hg)

146.1 ± 4.7

170.8 ± 21.1

< 0.001

Diastolic BP (mm Hg)

93.9 ± 4.9

107.0 ± 10.2

< 0.001

GA at delivery (weeks)

35.0 ± 4.2

34.0 ± 3.9

0.160