Journal of Clinical Gynecology and Obstetrics, ISSN 1927-1271 print, 1927-128X online, Open Access
Article copyright, the authors; Journal compilation copyright, J Clin Gynecol Obstet and Elmer Press Inc
Journal website http://www.jcgo.org

Original Article

Volume 5, Number 4, December 2016, pages 101-105


Serum Levels of Soluble Urokinase Plasminogen Activator Receptor Are Elevated in Severe Pre-Eclampsia

Figure

Figure 1.
Figure 1. Box plot of serum suPAR concentrations (interquartile ranges) subdivided into the three study groups. PE: 3.5 ng/mL (2.4 - 4.8 ng/mL). NP: 2.0 ng/mL (1.7 - 2.6 ng/mL). Control group: 2.3 ng/mL (1.9 - 2.9 ng/mL).

Tables

Table 1. Basic Characteristics of Patients With Pre-Eclampsia or Having a Normal Pregnancy
 
Pre-eclampsia (n = 10)Normal pregnancy (n = 9)P-value
SuPAR, ng/mL3.5 (2.4 - 4.8)2.0 (1.7 - 2.6)0.008
Age, years31 (26 - 36)29 (21 - 34)0.549
Gestational weeks, at sampling30.4 (28.4 - 34.3)31.1 (28.8 - 32.9)0.968
Gestational weeks, at birth30.9 (29.2 - 34.7)39.6 (38.3 - 39.8)< 0.001
Systolic blood pressure, highest, mm Hg180 (169 - 190)112 (108 - 120)< 0.001
Diastolic blood pressure, highest, mm Hg118 (108 - 120)71 (64 - 82)< 0.001
Birth weight, g1,427 (1,097 - 2,080)3,720 (3,280 - 4,256)0.001

 

Table 2. Severity of Pre-Eclampsia in the Pre-Eclampsia Group (Median and Interquartile Range (IQR))
 
MedianIQR
Daily urine protein, g3.71.7 - 8.5
Alanine aminotransaminase, U/L15718 - 590
Platelets, × 109/L175116 - 220
Uric acid, μmol/L423369 - 512
Cesarean section, days after sampling2.51.0 - 5.5
Apgar, 1 min8.56.5 - 9.0
Apgar, 5 min8.06.5 - 9.0