Journal of Clinical Gynecology and Obstetrics, ISSN 1927-1271 print, 1927-128X online, Open Access
Article copyright, the authors; Journal compilation copyright, J Clin Gynecol Obstet and Elmer Press Inc
Journal website http://www.jcgo.org

Case Report

Volume 8, Number 3, September 2019, pages 91-96


Fetal Heart Rate as an Indirect Indicator of Treatment Response in Fetal Hyperthyroidism Secondary to Transplacental Passage of Maternal Thyrotropin Receptor Antibodies

Figure

Figure 1.
Figure 1. Fetal heart rate (bpm) by estimated gestational age (weeks).

Tables

Table 1. Fetal and Maternal Testing
 
DateEGA (weeks)FHR (bpm)Levothyroxine (µg PO qDay)Methimazole (mg PO BID)TSH (µIU/mL)Free T4 (ng/mL)Free T3 (pg/mL)TRAb (U/L)TSI indexThyroid size (mm)EFW (g)EFW (percentile)
EGA: estimated gestational age; FHR: fetal heart rate; PO: per os; BID: twice daily; TSH: thyroid-stimulating hormone; TRAb: thyrotropin receptor antibody; TSI: thyroid-stimulating immunoglobulin; EFW: estimated fetal weight.
2014-12-1115 + 3-100-46.71.4------
2015-1-919 + 4154100-32.4-------
2015-2-223180175-------51825%
2015-2-323 + 1171175------17 × 8--
2015-2-523 + 3-175-12.61.17--447---
2015-2-1925 + 3162175-5.61.16--48118 × 9--
2015-3-227176175-------91115%
2015-3-1729 + 1180175105.141.27---19 × 10--
2015-3-2029 + 419217510-----23 × 13--
2015-3-2430 + 116217510-----24 × 14--
2015-3-2730 + 415720010-----21 × 131,42213%
2015-3-3131 + 116020010-----29 × 18--
2015-4-331 + 41572005--------
2015-4-6321572005--------
2017-4-732 + 11532005--------
2015-4-1032 + 416820055.491.192.478.6--1,90227%
2015-4-1433 + 116720010--------
2015-4-2134 + 116020010--------
2015-4-2434 + 415920010--------
2015-4-2835 + 116120010--------
2015-5-135 + 415320010------2,29712%
2015-5-536 + 115320010--------
2015-5-836 + 414920010--------
2015-5-1237 + 114320010--------
2015-5-1537 + 414420010--------
2015-5-1938 + 112820010--------
2015-5-2238 + 414020010------3,07527%
2015-5-2639 + 114120010--------
2015-5-2939 + 414320010--------
2015-6-240 + 1130200106.261.032---3,225-

 

Table 2. Neonatal Thyroid Testing
 
AgeTSI indexTSH (µIU/mL)Free T4 (ng/mL)
TSI: thyroid-stimulating immunoglobulin; TSH: thyroid-stimulating hormone.
Birth565< 0.037.05
1 Month1490.10.69
2 Months-0.850.86
3 Months581.071.04