Journal of Clinical Gynecology and Obstetrics, ISSN 1927-1271 print, 1927-128X online, Open Access
Article copyright, the authors; Journal compilation copyright, J Clin Gynecol Obstet and Elmer Press Inc
Journal website http://www.jcgo.org

Original Article

Volume 1, Number 4-5, October 2012, pages 71-75

Value of Serum β-hCG in Pathogenesis of Pre-Eclampsia

Figures

Figure 1.
Figure 1. Showing mean Serum β-hCG in normal pregnant mother, Mild and Severe Pre-eclampsia before and after delivery.
Figure 2.
Figure 2. Showing mechanism of rise of hCG.

Tables

Table 1. Clinical/Parameters of Both Control and PIH
 
ParameterNormal Pregnancy (control) (Mean ± SD) n = 50Pregnancy induced hypertension (PIH) (Mean ± SD) n = 50Significance
Age In Years22.36 ± 3.31 (18 - 32)21.62 ± 2.44 (18 - 30)Not significant (P = 0.172)
Systolic Blood Pressure in mmHg115.60 ± 7.93 (100 - 130)161.68 ± 18.25 (140 - 200)Significant (P ≤ 0.0001)
Diastolic Blood Pressure in mmHg73.08 ± 6.77 (60 - 90)103.20 ± 9.57 (90 - 120)Significant (P ≤ 0.0001)
Serum HCG in mIU/mL8,391.06 ± 1909.64 (5,366 - 10,939)18,087.42 ± 2,014.71 (12,456 - 21,649)Significant (P ≤ 0.0001)
Serum HCG after delivery3,377.06 ± 382.62 (2,467 - 4,329)3,491.12 ± 382.63 (2,800 - 3,882)Not significant (P ≤ 0.057)

 

Table 2. Clinical/Biochemical’s Parameters of Both Mild PIH and Severe PIH Mothers
 
ParameterMild PIHSevere PIHSignificance
Age In Years21.10 ± 1.97 (18 - 25)22.40 ± 2.90 (18 - 30)Non sufficient (P = 0.174)
Systolic Blood Pressure in mmHg149.20 ± 8.60 (140 - 170)180.40 ± 11.47 (160 - 200)Significant (P ≤ 0.0001)
Diastolic Blood Pressure in mmHg97.46 ± 5.48 (90 - 110)111.80 ± 7.78 (100 - 120)Significant (P ≤ 0.0001)
Serum HCG in mIU/mL16,950 ± 1,709.22 (12,456 - 19,369)19,793.40 ± 950 (17,549 - 21,649)Significant (P ≤ 0.0001)
Serum HCG after delivery3,494.43 ± 251.50 (2,900 - 3,882)3,486.15 ± 243.98 (2,800 - 3,874)Non Significant(P = 0.369)