Journal of Clinical Gynecology and Obstetrics, ISSN 1927-1271 print, 1927-128X online, Open Access
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Case Report

Volume 1, Number 1, February 2012, pages 19-23

Cutaneous Metastasis of Endometrial Carcinoma: A Case Report and Literature Review

Figures

Figure 1.
Figure 1. CT scan showing multiple subcutaneous nodules in the thoracic (A) and abdominal (B) of various sizes, referring first of metastatic lesions.
Figure 2.
Figure 2. Endometrial carcinoma. A: Hemalun-eosin staining, magnification 400 ×. B: Cytokeratin 7 positivity; C: Loss expression of PTEN; D: Estrogen receptor expression; E: Focal expression of progesterone receptor. Same immunohistochemical expression in both lesions compatible with a skin metastasis of the endometrioid carcinoma.
Figure 3.
Figure 3. Skin metastasis. A: Hemalun-eosin staining, magnification 400 ×; B: Cytokeratin 7 positivity; C: Loss expression of PTEN; D: Estrogen receptor expression; E: Focal expression of progesterone receptor. Same immunohistochemical expression in both lesions compatible with a skin metastasis of the endometrioid carcinoma.

Table

Table 1. Skin Metastasis of Endometrial Carcinoma: Review of Reports in the Literature [12].
 
Author, year of publicationAge (years)FIGO Stage/gradePrimary tumoral typeSiteOther metastasis at this time (Y/N)TherapyCutaneous metastasis to death
Rashbach et al 197853ICadenocarcinomaScalp, sacrum sternumNDoxorubicine cyclophosphamide6 month
Damewood et al 198053IB/G3Adenoepidermoid carcinomaHead , sacrum , left clavicleN3 month
Damewood et al 198058IVBMixed mesodermalscalpYMegace, adriamycineunknown
Debois 198250G3adenocarcinomaScalp, trunkYFew weeks
Debois 198256ICadenocarcinomaScalp , kneeYRadiation3 months
Kushmer et al 199756IC/G3Adenocarcinoma of endometriumscalpYDoxorubicine, cisplatine3 months
Present report , 200145IA/G2AdenocarcinomaScalp , craniumYCraniotomy6 months