Journal of Clinical Gynecology and Obstetrics, ISSN 1927-1271 print, 1927-128X online, Open Access
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Case Report

Volume 10, Number 2, June 2021, pages 55-58


A Case of a Rare Malignant Mixed Ovarian Germ Cell Tumor Masquerading as an Ectopic Pregnancy

Figures

Figure 1.
Figure 1. Laparoscopic view of the left ovarian mass presumed to be an ovarian ectopic.
Figure 2.
Figure 2. Histopathological assessment identified a malignant mixed ovarian germ cell tumor. Yolk sac tumor (a) and choriocarcinoma (b) components by H&E staining are shown. Original magnifications are × 100. H&E: hematoxylin and eosin stain.

Table

Table 1. Comparison of Clinical Findings and Management of Malignant Ovarian Germ Cell Tumors Presenting as Apparent Ectopic Pregnancies
 
ReferenceHistologySymptomsInvestigationsManagement
USS: ultrasound; β-hCG: beta-human chorionic gonadotrophin; TVS: transvaginal ultrasound; CT: computed tomography; AFP: alpha fetoprotein; TVUS: transvaginal ultrasound.
Kucera et al, 2017 [4]Mixed germ cell tumorAmenorrhoeaLeft adnexal mass on USS, β-hCG: 2,121Laparoscopy
Rozenholc et al, 2012 [3]Mixed germ cell tumorAmenorrhoea, right abdominal tendernessRight adnexal mass on USS, β-hCG: 11,998Laparoscopy
Ozkaya et al, 2005 [5]Mixed germ cell tumorAmenorrhoea, abdominal painLeft adnexal mass on TVS and CT scan, raised AFP 2,172, β-hCG: 3,800Exploratory laparotomy
Dawley et al, 2012 [6]Mature teratomaAmenorrhoeaNo intrauterine pregnancy on TVS, β-hCG: 57,914Laparoscopy
Balat et al, 2004 [7]Ovarian choriocarcinomaIrregular vaginal bleedingMass on TVS, β-hCG: 8.968Exploratory laparotomy
Freij et al, 2011 [8]Ovarian choriocarcinomaLower abdominal painLeft ovarian mass on TVUS, β-hCG: 1,110.5Laparoscopy
Horne et al, 2006 [9]Ovarian choriocarcinomaLower abdominal pain, heavy vaginal bleedingRight adnexal mass on TVUS, static β-hCG: 189Methotrexate initially, laparoscopy when rising β-hCG