| Journal of Clinical Gynecology and Obstetrics, ISSN 1927-1271 print, 1927-128X online, Open Access |
| Article copyright, the authors; Journal compilation copyright, J Clin Gynecol Obstet and Elmer Press Inc |
| Journal website https://www.jcgo.org |
Review
Volume 11, Number 2, June 2022, pages 23-26
Recurrent First Trimester Miscarriage: A Typical Case Presentation and Evidence-Based Management Review
Table
| Cause | Test |
|---|---|
| Genetic-balanced chromosomal translocations | Karyotyping of products of conception (if abnormal result detected - parental karyotyping) |
| Antiphospholipid syndrome | Blood test for anticardiolipin antibodies and/or lupus anticoagulant (blood tests should be performed at least 6 weeks after any pregnancy loss and a repeat confirmatory test should be arranged at least 12 weeks after an initial positive screen) |
| Endocrine (if evidence of clinical disorder or risk factors): thyroid, diabetes | Thyroid function test (serum free T4 and thyroid-stimulating hormone levels); thyroid peroxidase antibodies; HbA1c |
| Uterine abnormalities such as septate uterus or intracavitary lesions | Transvaginal ultrasound scan |